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ersiliaos/eos7jur

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By Ersilia Open Source Initiative

Updated 6 days ago

Ersilia Model Hub Identifier: eos7jur

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ersiliaos/eos7jur repository overview

RetroMol Biosynthetic Fingerprint

Decomposes a natural product into the biosynthetic building blocks its assembly line would have used, returning a 452-dimensional count vector over monomer tokens spanning polyketide extender units, amino acids and tailoring modifications. RetroMol was built to give natural products and their biosynthetic gene clusters a shared encoding, and applies curated retrobiosynthetic rules rather than a trained model, so output is fully deterministic. A coverage value reports how much of the molecule was parsed; compounds outside modular polyketide and nonribosomal peptide chemistry parse poorly.

This model was incorporated on 2026-09-18.Last packaged on 2026-09-18.

Information

Identifiers
  • Ersilia Identifier: eos7jur
  • Slug: retromol-fingerprint
Domain
  • Task: Representation
  • Subtask: Featurization
  • Biomedical Area: Any
  • Target Organism: Any
  • Tags: Fingerprint, Natural product, Descriptor
Input
  • Input: Compound
  • Input Dimension: 1
Output
  • Output Dimension: 453
  • Output Consistency: Fixed
  • Interpretation: Weights of 451 biosynthetic building-block tokens plus an unidentified-monomer bin and a coverage fraction.

Below are the Output Columns of the model:

NameTypeDirectionDescription
feat_000floathighAccumulated weight of monomers that no matching rule could identify
feat_001floathighAccumulated weight of the 1-(1-1-dimethylallyl)-tryptophan biosynthetic building block token
feat_002floathighAccumulated weight of the 1-aminocyclopropane-1-carboxylic acid biosynthetic building block token
feat_003floathighAccumulated weight of the 1-pyrroline-5-carboxylic acid biosynthetic building block token
feat_004floathighAccumulated weight of the 10-14-dimethyloctadecanoic acid biosynthetic building block token
feat_005floathighAccumulated weight of the 2-2-dimethylpropanoic acid biosynthetic building block token
feat_006floathighAccumulated weight of the 2-3-diaminobutyric acid biosynthetic building block token
feat_007floathighAccumulated weight of the 2-3-diaminopropionate biosynthetic building block token
feat_008floathighAccumulated weight of the 2-3-dihydroxy-para-aminobenzoic acid biosynthetic building block token
feat_009floathighAccumulated weight of the 2-3-dihydroxybenzoic acid biosynthetic building block token

10 of 453 columns are shown

Source and Deployment
Resource Consumption
  • Model Size (Mb): 1
  • Environment Size (Mb): 931
  • Image Size (Mb): 940.12

Computational Performance (seconds):

  • 10 inputs: 28.96
  • 100 inputs: 21.29
  • 10000 inputs: 249.73
References
License

This package is licensed under a GPL-3.0 license. The model contained within this package is licensed under a MIT license.

Notice: Ersilia grants access to models as is, directly from the original authors, please refer to the original code repository and/or publication if you use the model in your research.

Use

To use this model locally, you need to have the Ersilia CLI installed. The model can be fetched using the following command:

# fetch model from the Ersilia Model Hub
ersilia fetch eos7jur

Then, you can serve, run and close the model as follows:

# serve the model
ersilia serve eos7jur
# generate an example file
ersilia example -n 3 -f my_input.csv
# run the model
ersilia run -i my_input.csv -o my_output.csv
# close the model
ersilia close

About Ersilia

The Ersilia Open Source Initiative is a tech non-profit organization fueling sustainable research in the Global South. Please cite the Ersilia Model Hub if you've found this model to be useful. Always let us know if you experience any issues while trying to run it. If you want to contribute to our mission, consider donating to Ersilia!

Tag summary

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sha256:f195cd26b

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325.6 MB

Last updated

6 days ago

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